What are the common side effects of colchicine?

美加子 里佳
美加子 里佳
Medical student studying chronic inflammatory conditions.

Hey friend, speaking of colchicine, it's quite effective for treating gout, but you really need to pay attention to the side effects.

The most common are gastrointestinal reactions. Simply put, after taking it, you're prone to nausea, vomiting, stomach pain, and especially diarrhea. Many people experience this when they first start taking it, which is why doctors usually advise starting with a small dose, or immediately stopping or reducing the dose if diarrhea occurs. Basically, this is your body telling you the dosage might be a bit too high.

Besides these, there are some less common but serious situations to be aware of:

  1. Muscle problems: You might feel muscle weakness and soreness. If you're also taking statins for high cholesterol (like atorvastatin, rosuvastatin), this risk is even higher. If you feel unusually weak or have abnormal muscle pain, it's best to consult a doctor.
  2. Numbness in hands and feet: Some people might feel tingling or numbness in their fingers and toes.
  3. Long-term effects: If you need to take it for a long time, your doctor might ask you to have regular blood tests, as it can affect bone marrow hematopoietic function. However, this is relatively rare and usually only a concern with long-term, high-dose use.

In short, this medicine is effective, but it shouldn't be taken carelessly. Always strictly follow your doctor's prescribed dosage and timing, and never increase the dose on your own. If you experience any discomfort, especially those mentioned above, the safest course of action is to immediately consult your doctor or pharmacist.