What are the hazards of diabetes to the kidneys?

Created At: 8/13/2025Updated At: 8/17/2025
Answer (1)

Okay, no problem. Let's talk about this in plain language.


Here's how to understand the harm diabetes does to the kidneys:

Hi! Seeing you're concerned about this shows you're very health-conscious. The relationship between diabetes and the kidneys is indeed very close, and this damage is "silent and insidious" – it's hard to detect early, so it especially requires our attention.

Think of our kidneys as a super-precise filter. Its main job is to filter out "waste" from the blood (like metabolic byproducts, excess water) to form urine and expel it, while keeping the useful stuff (like proteins, blood cells) inside.

Diabetes, especially when blood sugar is poorly controlled, causes continuous damage to this "filter".

1. The Filter is Under Huge Pressure, and the Mesh Gets Ruined

When blood sugar is very high, the blood becomes "thicker" and "stickier" than usual. Imagine water flowing easily through a filter screen, but what about syrup? It would be much harder.

  • High-Pressure Flushing: To pump this sticky blood through and complete the filtration, the tiny blood vessels in the kidneys (finer than a hair, called glomeruli – essentially the "filter mesh") have to withstand enormous pressure.
  • Mesh Deformation: Being constantly "flushed" under high pressure over the years, this delicate "mesh" slowly gets stretched, deformed, and can even develop tears.

2. From "Leaking Protein" to "Shutdown" – How Does it Happen?

This damage doesn't happen overnight; it usually progresses through several stages:

  • Stage 1 (Early): Sneaky "Leaks"

    • At first, the holes in the "mesh" get stretched just a little. Some "good stuff" that should stay in the blood – microalbumin – starts leaking into the urine through the gaps.
    • This stage is the golden warning period! Because you won't feel any discomfort at all, but a test called "urine microalbumin" can detect it. If you intervene effectively at this point, it can often be reversed or significantly slowed down.
  • Stage 2 (Mid-Stage): Holes Get Bigger

    • If blood sugar control remains poor, the "holes" in the mesh get larger, leaking more and more protein. Foam in the urine also becomes noticeably more persistent (like beer foam that doesn't disappear easily).
    • At this point, the kidney's filtering function starts to genuinely decline. Blood pressure also often rises, further damaging the kidneys and creating a vicious cycle.
  • Stage 3 (Late Stage): The Filter is Basically "Trashed"

    • By this stage, large amounts of the "filter mesh" have hardened and died off, unable to work properly. The kidney's ability to clear toxins from the blood is severely reduced.
    • "Waste" builds up in the body because it can't be expelled, leading to various unpleasant symptoms like nausea, vomiting, extreme fatigue, itchy skin, and severe swelling (edema). This is what we commonly call "kidney failure" or "uremia/end-stage renal disease (ESRD)".
  • End-Stage: Needing an "Artificial Kidney"

    • Once it progresses to uremia/ESRD, it means the kidneys have completely "shut down." To survive, one must rely on external methods to replace kidney function, namely hemodialysis (dialysis) or kidney transplantation.

3. Don't Panic! What Can We Do to Protect Our Kidneys?

Talking about all these harms isn't meant to scare you, but to remind us that the initiative to protect our kidneys is actually in our own hands.

  1. Control Blood Sugar is Fundamental: This is the single most important measure! Keeping your HbA1c (a measure of average blood sugar over 3 months) within the target range directly "lightens the load" on your kidneys.
  2. Control Blood Pressure and Cholesterol: High blood pressure is an "accomplice" that speeds up kidney damage. Many people with diabetes also have high blood pressure, so managing both sugar and pressure is crucial.
  3. Regular Check-ups are the "Sentinels": Even if you feel perfectly fine, listen to your doctor and get checked at least once a year:
    • Urine Microalbumin: This is the "radar" for detecting early kidney damage.
    • Serum Creatinine: This allows estimation of your kidney function (eGFR).
  4. Healthy Lifestyle:
    • Diet: Low salt, moderate protein. If kidney problems are already present, strictly follow your doctor's advice on limiting protein and salt.
    • Medications: Don't take painkillers or unproven herbal remedies indiscriminately. Many drugs harm the kidneys; always consult your doctor before taking anything.
    • Stay Hydrated: Ensure adequate fluid intake, but if swelling occurs, follow your doctor's guidance.
    • Don't Smoke: Smoking worsens damage to kidney blood vessels.

To Summarize:

The harm diabetes does to the kidneys is like "boiling a frog slowly" – there are no symptoms initially, but by the time you feel something, it's often quite serious.

Remember this progression: High Blood Sugar → Damages the Kidney "Filter" → Protein Leaks → Kidney Function Declines → Kidney Failure/Uremia.

Therefore, for everyone with diabetes, managing blood sugar and blood pressure well, and giving your kidneys an annual "check-up" (urine microalbumin + serum creatinine), is the best way to protect them. As long as we take it seriously and manage it actively, we can greatly minimize the risk of reaching the worst-case scenario.

Created At: 08-13 13:29:05Updated At: 08-13 16:51:11